What Can You Do in 48 Hours in San Antonio?

Looking for a quick and exciting weekend escape? 48 Hours in San Antonio is all you need to experience history, culture, food, and charm—Texas style. This vibrant city blends Spanish heritage with modern flair, offering something for every traveler. From walking through centuries-old missions to tasting unforgettable Tex-Mex and BBQ, San Antonio is packed with highlights. Whether you’re strolling the River Walk, exploring colorful markets, or dining at rooftop restaurants, every moment is memorable. Let’s make the most of it.

Day 01

Morning

Start your day with a visit to The Alamo, one of the most famous landmarks in San Antonio, Texas. This historic site was once known as Mission San Antonio de Padua and played a key role in the fight for Texas independence. It’s a part of the larger network of San Antonio Missions, a UNESCO World Heritage Site that preserves the city’s colonial roots. Just a short walk away is the San Fernando Cathedral, one of the oldest cathedrals in the United States. It’s a beautiful spot to take in early morning views and learn more about San Antonio’s spiritual history.

Late Morning

Next, head to the River Walk San Antonio, a lively pathway that winds along the river through the heart of the city. The River Walk is lined with restaurants and shops, making it a great place to grab a coffee or do a little browsing.

Enjoy the cool shade from the trees, listen to the sound of nearby fountains, and admire public art along the way. Whether you walk or just sit by the water, this area is a peaceful yet vibrant escape in the middle of downtown.

Afternoon

To see more of the city from a new angle, hop aboard a Rio River Cruise. These narrated River Walk cruises are fun, relaxing, and full of interesting facts. You’ll learn about San Antonio’s architecture, landmarks, and culture—all while floating past the scenic views of the River Walk.

Lunch

There are many great restaurants and shops along the River Walk, including local favorites like Boudro’s and Casa Rio. Enjoy Tex-Mex dishes, refreshing drinks, and waterfront views as you recharge for the rest of the day. It’s one of the most popular places to eat in San Antonio, Texas, especially if you love lively energy.

Evening

In the evening, make your way to the Pearl Brewery. Once a historic brewery, this area is now a trendy spot filled with dining, art, and music. You can enjoy dinner at places like Supper, grab dessert, or sip cocktails in the open air.

The Pearl Brewery is perfect for a casual stroll as the sun sets. You’ll find cozy patios, creative food options, and live music depending on the night.

Day 2

Morning

Start your Saturday morning at the Pearl Farmers Market, a lively open-air gathering near the Pearl Brewery. Locals and visitors come here for fresh produce, handmade crafts, and tasty treats.

Grab a cup of coffee at Local Coffee, a popular spot with a bright and cozy vibe. Pair it with a warm pastry as you stroll through vendor stalls filled with everything from honey to baked goods and fresh flowers.

Late Morning

After the market, dive deeper into history with a guided tour or bike ride along the San Antonio Missions Trail. These missions are part of a UNESCO World Heritage Site and showcase over 300 years of local history.

Visit Mission San José, known as the “Queen of the Missions,” and the peaceful Mission Concepción, both beautiful examples of Spanish colonial architecture. Each mission san along the trail offers a different glimpse into Texas’s past.

Afternoon

Spend the afternoon exploring the art and nature scene of San Antonio, Texas. You can visit the McNay Art Museum, which features modern works inside a Spanish colonial mansion. Or check out the San Antonio Museum of Art (SAMA) along the river for collections from around the world.

If you prefer being outdoors, stroll through the Japanese Tea Garden or the San Antonio Botanical Garden. Both are peaceful spots perfect for relaxing, snapping photos, or just enjoying a few quiet hours in San Antonio.

Dinner

Wrap up your 48-hour adventure with a memorable dinner. For rooftop vibes and city views, head to The Moon’s Daughters at the Thompson Hotel. Their Mediterranean small plates and creative cocktails make for a stylish evening out.

If you prefer something cozy and elegant, try Supper at Hotel Emma, where farm-to-table dishes shine in a relaxed yet upscale setting.

Both restaurants are located near the Pearl Brewery and surrounded by inviting restaurants and shops—making it easy to take a post-dinner stroll and soak in your final night in San Antonio, Texas.

Bonus Stops

Blue Star Arts Complex

If you have extra time during your trip to San Antonio, visit the Blue Star Arts Complex. This creative space is filled with art galleries, studios, local shops, and restaurants. It's a great place to see local artists at work and admire unique exhibits. You can also enjoy a casual meal or coffee while exploring the area.

King William Historic District

Take a stroll through the King William Historic District, one of the most beautiful neighborhoods in the city. This area is known for its grand 19th-century homes, leafy streets, and quiet charm. You’ll also find local cafes and art galleries along the way. It’s perfect for a peaceful afternoon walk during your 48 hours in San Antonio.

Market Square

For lively energy and colorful culture, head to Historic Market Square. This is the largest Mexican market in the United States. Here you can shop for handcrafted goods, try Tex-Mex favorites, and enjoy live music. It’s a fun and festive stop that brings even more flavor to your trip to San Antonio.

Final Thoughts

San Antonio, Texas is a city that blends history, culture, food, and natural beauty like few others. From ancient missions and modern art to rooftop dining and riverside strolls, every moment offers something special. In just 48 hours in San Antonio, you can explore centuries of history, taste bold local flavors, and discover hidden gems throughout the city.

Whether you're here for the first time or returning for more, there’s always something new to enjoy. With so many things packed into one weekend, this city makes every minute count.